Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.36 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.36 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884001 | 0.90 | PPARG (0.37) | PPARGAKR1C3AKR1C2CYP11B1CYP11B2 | |
| SCHEMBL3883891 | 0.90 | XDH (0.39) | PPARGAKR1C3AKR1C2PLA2G10PLA2G2A | |
| SCHEMBL3889928 | 0.88 | PPARG (0.37) | PPARGAKR1C3AKR1C2CYP11B1CYP11B2 | |
| SCHEMBL3885031 | 0.88 | MYC (0.42) | AKR1C3AKR1C2PLA2G10PLA2G2APTGER1 | |
| SCHEMBL3884288 | 0.87 | AKR1C3 (0.41) | PPARGAKR1C3AKR1C2PTGER1PTGER4 | |
| SCHEMBL3882989 | 0.86 | AKR1C3 (0.38) | AKR1C3AKR1C2PLA2G10PLA2G2APTGER1 | |
| SCHEMBL3882946 | 0.86 | PPARG (0.40) | PPARGAKR1C3AKR1C2PLA2G10PLA2G2A | |
| SCHEMBL3885728 | 0.86 | FFAR1 (0.48) | CYP11B1CYP11B2CYP19A1HDAC1 | |
| SCHEMBL3883495 | 0.85 | PLA2G10 (0.40) | PPARGAKR1C3AKR1C2CYSLTR2CYSLTR1 | |
| SCHEMBL3891606 | 0.85 | PTGER1 (0.39) | AKR1C3AKR1C2PLA2G10PLA2G2APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |