Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317626 | 0.97 | DGKA (0.43) | TSHRDGKALMNAALDH1A1PAM | |
| SCHEMBL15512804 | 0.88 | DGKA (0.42) | TSHRDGKANPC1LMNAALDH1A1 | |
| SCHEMBL536517 | 0.87 | ALDH1A1 (0.42) | TSHRDGKANPC1LMNAALDH1A1 | |
| SCHEMBL1498053 | 0.85 | ALDH1A1 (0.44) | DGKANPC1LMNAALDH1A1PAM | |
| SCHEMBL28493170 | 0.84 | TSHR (0.50) | TSHRDGKANPC1SLC22A6ALDH1A1 | |
| SCHEMBL29308246 | 0.83 | DGKA (0.61) | TSHRDGKALMNAALDH1A1PAM | |
| SCHEMBL29582411 | 0.83 | DGKA (0.61) | TSHRDGKALMNAALDH1A1PAM | |
| SCHEMBL21266960 | 0.83 | DGKA (0.61) | TSHRDGKALMNAALDH1A1PAM | |
| SCHEMBL10555566 | 0.82 | TSHR (0.48) | TSHRSLC22A6LMNAALDH1A1 | |
| SCHEMBL23159109 | 0.81 | DGKA (0.65) | DGKALMNAALDH1A1PAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979397-A4 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RES GROUP INC (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1979397-A2 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008051241-A2 | SHAPE MEMORY CYANATE ESTER COPOLYMERS | CORNERSTONE RESEARCH GROUP, INC. (US) | 2008-05-02 | — | — | WO | disclosed |