SCHEMBL3884

SCHEMBL3884

[C]1CCCc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
MAOA P21397 3/20 0.35
MAOB P27338 3/20 0.35
CYP2A6 P11509 1/20 0.35
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTR2C P28335 1/20 0.32
NOS3 P29474 1/20 0.31
BCL2L1 Q07817 1/20 0.31
BAD Q92934 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
KIF11 P52732 1/20 0.31
IDO1 P14902 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL286696 1.00 TSHR (0.48) TSHRMAOAMAOBCYP2A6MAPT
SCHEMBL9421049 0.93 TSHR (0.52) TSHRMAOAMAOBCYP2A6MAPT
SCHEMBL62945 0.93 TSHR (0.52) TSHRMAOAMAOBCYP2A6MAPT
SCHEMBL177122 0.91 TSHR (0.50) TSHRMAOAMAOBCYP2A6MAPT
SCHEMBL21267 0.85
SCHEMBL1374665 0.85
SCHEMBL2952083 0.83 MAOA (0.44) TSHRMAOAMAOBCYP2A6MAPT
SCHEMBL3543729 0.76 TSHR (0.32) TSHR
SCHEMBL42412 0.74 MEN1 (0.36) TSHR
SCHEMBL1098772 0.73 TSHR (0.50) TSHRMAOAMAOBCYP2A6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 105737 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432995-B1 None US claimed
US-12043634-B2 Metal complexes, methods of making the same, and uses thereof THE UNIVERSITY OF MANITOBA (CA) 2024-07-23 US claimed
US-20240238264-A1 INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF DISARM THERAPEUTICS, INC. 2024-07-18 US claimed
CN-118354995-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-07-16 CN claimed
CN-118324686-A Diazacyclo compound, cyclic trimethylcyanine compound, preparation methods thereof, imaging agent and application 南京大学 2024-07-12 CN claimed
CN-118324816-A Organometallic compound, light-emitting device, electronic apparatus, and electronic device 三星显示有限公司 2024-07-12 CN claimed
CN-118339142-A Novel compound and organic light emitting device using the same 株式会社LG化学 2024-07-12 CN claimed
WO-2024148274-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2024-07-11 WO claimed
WO-2024147306-A1 AMIDE COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME 住友化学株式会社 2024-07-11 WO claimed
EP-4397664-A1 PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF Genfleet Therapeutics (Shanghai) Inc. (CN) 2024-07-10 EP claimed
US-4000274-A PHARMACEUTICAL COMPOSITIONS CONTAINING AN N-ARYL-N'-(PHENYL-OR-PHENOXY-ALKYL)-PIPERAZINE AND METHOD OF USE BOEHRINGER INGELHEIM GMBH (DT) 1976-12-28 US claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed
US-3996284-A Naphthyl and tetrahydronaphthyl di-ethers NAUTA WIJBE THOMAS 1976-12-07 US claimed
US-3984460-A LIGHT AND HEAT STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-10-05 US claimed
US-3971804-A ACARICIDES, FUNGICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US claimed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US claimed
US-3962377-A PHOTOCHEMICAL, OXIDATIVE, AND THERMAL STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-06-08 US claimed
US-3954839-A LIGHT AND HEAT STABILIZERS FOR POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-05-04 US claimed
US-3941789-A CNS DEPRESSANT, ADRENOLYTIC, ANTIPHLOGISTIC, ANALGESIC, ANTIHISTAMINE, ANTICHOLESTEROL BOEHRINGER INGELHEIM GMBH (DT) 1976-03-02 US claimed
US-3939207-A Method for preparing aldehydes ESCHENMOSER ALBERT 1976-02-17 US claimed