SCHEMBL3884017

SCHEMBL3884017

Cc1ccc(S(=O)(O)(O)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
LMNA P02545 3/20 0.43
ACHE P22303 2/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 4/20 0.38
AKR1C3 P42330 1/20 0.38
HPGD P15428 2/20 0.38
HSD11B1 P28845 1/20 0.38
POLB P06746 1/20 0.37
EGFR P00533 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3884170 0.91 TDP1 (0.44) CES2CES1LMNAACHETSHR
SCHEMBL278265 0.85 TSHR (0.39) CES2CES1TSHRSMN1; SMN2ALDH1A1
Benzene SCHEMBL28958130 0.85 TSHR (0.39) CES2CES1TSHRSMN1; SMN2ALDH1A1
SCHEMBL3883006 0.81 ACHE (0.42) LMNAACHETSHRALOX12MEN1
SCHEMBL776257 0.77 KCNN4 (0.38) CES2CES1NPC1RAB9AMEN1
SCHEMBL11082106 0.76 CA1 (0.46) LMNATSHRNPC1RAB9ASMN1; SMN2
SCHEMBL776892 0.75 CES2 (0.53) CES2CES1LMNANPC1RAB9A
SCHEMBL3892065 0.74 TSHR (0.36) ACHETSHRNPC1RAB9AKMT2A
SCHEMBL3883735 0.73 TDP1 (0.42) CES2CES1LMNAACHETSHR
SCHEMBL3896461 0.73 ACHE (0.48) LMNAACHETSHRKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed