Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891048 | 0.88 | MAPK14 (0.41) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3881923 | 0.88 | MAPK14 (0.40) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3889253 | 0.88 | MAPK14 (0.40) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3888233 | 0.85 | TRPA1 (0.40) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3882061 | 0.85 | FFAR4 (0.45) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3895963 | 0.84 | IKBKB (0.42) | ROCK1AKT1PDE4APDE4BPDE4C | |
| SCHEMBL3883918 | 0.83 | TRPA1 (0.38) | TRPA1ROCK2GSK3BCDK5DYRK1A | |
| SCHEMBL3884504 | 0.83 | AR (0.43) | TRPA1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3884038 | 0.82 | TRPA1 (0.42) | TRPA1ROCK2PDE4APDE4BPDE4C | |
| SCHEMBL3888551 | 0.81 | FFAR4 (0.39) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |