Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881923 | 1.00 | MAPK14 (0.40) | MAPK14TRPA1BCL9CTNNB1CTSC | |
| SCHEMBL3891048 | 0.99 | MAPK14 (0.41) | MAPK14TRPA1BCL9CTNNB1CTSC | |
| SCHEMBL3883580 | 0.92 | BCL9 (0.40) | BCL9CTNNB1CTSCFGFR1ADRB1 | |
| SCHEMBL3884002 | 0.88 | F11 (0.40) | MAPK14TRPA1CTSCROCK2DYRK1A | |
| SCHEMBL3884035 | 0.88 | TRPA1 (0.42) | MAPK14TRPA1ROCK2DYRK1AAURKA | |
| SCHEMBL3883671 | 0.85 | PTGS2 (0.43) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3882042 | 0.84 | PTGS2 (0.43) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3884902 | 0.84 | FFAR4 (0.48) | MAPK14TRPA1BCL9CTNNB1CTSC | |
| SCHEMBL3881066 | 0.84 | FFAR4 (0.48) | MAPK14TRPA1BCL9CTNNB1CTSC | |
| SCHEMBL3893294 | 0.84 | MAPK14 (0.41) | MAPK14TRPA1ROCK2DYRK1AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |