Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | PI4KA | P42356 | 7/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.47 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883688 | 0.82 | PPARD (0.45) | SCN4AEPHX2CYP3A4PI4KAPI4KB | |
| SCHEMBL17969171 | 0.77 | SCN4A (0.77) | SCN4AEPHX2CYP3A4PI4KAPI4KB | |
| SCHEMBL1853965 | 0.75 | CYP3A4 (0.62) | CYP3A4PI4KAPI4KBPIK3CAPIK3CD | |
| SCHEMBL25261274 | 0.75 | PIK3CA (0.60) | SCN4AEPHX2CYP3A4PI4KAPI4KB | |
| SCHEMBL31347459 | 0.75 | PI4KA (0.60) | CYP3A4PI4KAPI4KBPIK3CAPIK3CD | |
| SCHEMBL31114755 | 0.75 | PIK3CA (0.60) | SCN4AEPHX2CYP3A4PI4KAPI4KB | |
| SCHEMBL3883099 | 0.73 | FFAR4 (0.47) | CYP3A4PIK3CAKCNH2TP53 | |
| SCHEMBL13762819 | 0.72 | RXRA (0.48) | RXRARXRBRXRG | |
| SCHEMBL1417399 | 0.71 | SCN4A (1.00) | SCN4AEPHX2CYP3A4PI4KAPI4KB | |
| SCHEMBL3882518 | 0.71 | TRPA1 (0.58) | RXRARXRBRXRGSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |