Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885151 | 0.87 | PPARG (0.38) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3895497 | 0.87 | FFAR4 (0.46) | PTGER4PTGER3FFAR4PTGESRAPGEF3 | |
| SCHEMBL3884001 | 0.86 | PPARG (0.37) | AKR1C3AKR1C2FFAR1PPARGPPARD | |
| SCHEMBL3894677 | 0.86 | AKR1C3 (0.43) | AKR1C3AKR1C2PTPN1PTGER1PTGER4 | |
| SCHEMBL3883891 | 0.86 | XDH (0.39) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL6392023 | 0.85 | CCNC (0.45) | AKR1C3AKR1C2PTPN1FFAR4PTPN2 | |
| SCHEMBL3889928 | 0.84 | PPARG (0.37) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3885031 | 0.84 | MYC (0.42) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3882989 | 0.83 | AKR1C3 (0.38) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3882946 | 0.82 | PPARG (0.40) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |