SCHEMBL3884328

SCHEMBL3884328

C=CC(=O)NC(CC)C(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
ACACB O00763 2/20 0.35
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
TGM2 P21980 1/20 0.32
CYP2C19 P33261 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9138528 0.86 TSHR (0.42) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL3165262 0.84 TSHR (0.44) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9136665 0.84 TAS1R3 (0.35) ACACB
SCHEMBL9136660 0.84 TAS1R3 (0.35) ACACB
SCHEMBL9138073 0.83 ZDHHC20 (0.41) TSHRACACBZDHHC20ZDHHC2TGM2
SCHEMBL9139050 0.82 TSHR (0.47) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9139457 0.82 TSHR (0.42) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9136680 0.82 ZDHHC20 (0.44) TSHRMAPK1ZDHHC20ZDHHC2TGM2
SCHEMBL8054714 0.81 TSHR (0.41) TSHRACACBALDH1A1MAPK1TDP1
SCHEMBL9138566 0.81 TSHR (0.41) TSHRACACBALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197919-B1 ADDITION POLYMERIZATION OF ANIONIC AND CATIONIC MONOMERS; CHAIN TRANSFER HERCULES INCORPORATED 2001-03-06 US claimed
US-5961763-A Sealable nonwoven web AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-10-05 US claimed
EP-0915918-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1999-05-19 EP claimed
WO-1998054237-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1998-12-03 WO claimed
US-5180772-A Solvent resistance, disposable products AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-01-19 US claimed
EP-0421244-A2 Process for making an acrylamide containing a dialkyl acetal group AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-04-10 EP claimed
US-4959489-A MICHAEL ADDITION, AMINATION, BLOCKING, PYROLYSIS AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-09-25 US claimed
JP-5331122-A None JP disclosed
CN-111821503-B Radiopaque high-efficiency drug-loaded embolism microsphere and preparation and application thereof 苏州恒瑞宏远医疗科技有限公司 2022-07-12 CN disclosed
CN-111821503-A Radiopaque high-efficiency drug-loaded embolism microsphere and preparation and application thereof 苏州恒瑞宏远医疗科技有限公司 2020-10-27 CN disclosed
EP-1589138-B1 Improvement in the wet tensile strength of nonwoven webs WACKER CHEMICAL CORP (US) 2009-07-22 EP disclosed
EP-1589139-B1 Nonwovens with binders of high wet/dry tensile strength ratio WACKER CHEMICAL CORP (US) 2009-01-14 EP disclosed
US-7285504-B2 Flushes, disperses and finally biodegrades, pre-moistened nonwoven wet wipe AIR PRODUCTS POLYMERS, L.P. (US) 2007-10-23 US disclosed
US-4691026-A Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-01 US disclosed
US-4663410-A Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-05-05 US disclosed
EP-0218827-A2 Polymers of self- and diol reactive formaldehyde-free crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-04-22 EP disclosed
EP-0215245-A1 Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers and their derived polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-03-25 EP disclosed
US-4647611-A Trail addition of acrylamidobutyraldehyde dialkyl acetal-type monomers during the polymerization of vinyl acetate copolymer binders AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-03-03 US disclosed
EP-0211432-A2 Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-02-25 EP disclosed
EP-0201693-A2 Self- and diol reactive formaldehyde-free crosslinking monomers and their derived polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-20 EP disclosed