Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.48 |
| ▸ | GABRD | O14764 | 4/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.48 |
| ▸ | GABRE | P78334 | 4/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26624384 | 0.85 | ACHE (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22500622 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22500624 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17021602 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL900319 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL900317 | 0.82 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3884473 | 0.81 | — | — | |
| SCHEMBL28481207 | 0.80 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6570484 | 0.78 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8965248 | 0.78 | ACHE (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571165-B1 | Compositions for the preparation of hydrophobic coatings | TOFFANO LORENZO (IT) | 2009-01-07 | — | — | EP | disclosed |
| EP-1571165-A1 | Compositions for the preparation of hydrophobic coatings | Toffano, Lorenzo (IT) | 2005-09-07 | — | — | EP | disclosed |