Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423530 | 0.71 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL518737 | 0.69 | TDP1 (0.60) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL2085135 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL101 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Benzene SCHEMBL6890099 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL5028587 | 0.69 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL25384985 | 0.67 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL22558063 | 0.67 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL1195618 | 0.67 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL20582981 | 0.67 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120122-A1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | PUGIN BENOIT (CH) | 2003-06-26 | — | — | US | claimed |
| EP-1002801-B1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | SOLVIAS AG (CH) | 2003-06-18 | — | — | EP | claimed |
| US-6515183-B2 | Hydrogenation catalyst | SOLVIAS AG (CH) | 2003-02-04 | — | — | US | claimed |
| US-20010056210-A1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | PUGIN BENOIT (CH) | 2001-12-27 | — | — | US | claimed |
| EP-1002801-A1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | Solvias AG (CH) | 2000-05-24 | — | — | EP | claimed |
| JP-10001491-A | — | — | None | — | — | JP | disclosed |
| WO-2023074258-A1 | ACTIVE ESTER COMPOUND | 東洋紡株式会社 | 2023-05-04 | — | — | WO | disclosed |
| WO-2023021900-A1 | ACTIVE ESTER COMPOUND | 東洋紡株式会社 | 2023-02-23 | — | — | WO | disclosed |
| CN-114685408-A | Preparation method of alkyl furan compound | 华南理工大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110540552-A | Aromatic phosphorus oxide compound and preparation method of aromatic phosphorus oxide medicine thereof | UNIV HUNAN | 2019-12-06 | — | — | CN | disclosed |
| CN-105392776-B | Thio-Salalen catalyst | 埃克森美孚化学专利公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-105377905-B | Metallocenes and catalyst compositions derived therefrom | 埃克森美孚化学专利公司 | 2018-09-14 | — | — | CN | disclosed |
| US-5801287-A | Substituted diphenyldiphosphines and a process for their preparation | AVENTIS RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) | 1998-09-01 | — | — | US | disclosed |
| US-5746155-A | Water treatment with large numbers of non-pathogenic bacteria to improve yield of aquatic animals | LOGAN WALTER T (US) | 1998-05-05 | — | — | US | disclosed |
| JP-H101491-A | SUBSTITUTED DIPHENYLDIPHOSPHINE COMPOUND AND ITS PRODUCTION | HOECHST AG | 1998-01-06 | — | — | JP | disclosed |
| EP-0795533-A1 | Process for the preparation of aldehydes using a catalyst system containing rhodium and substituted diphenyldiphosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0795533-A1 | Process for the preparation of aldehydes using a catalyst system containing rhodium and substituted diphenyldiphosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0795533-A1 | Process for the preparation of aldehydes using a catalyst system containing rhodium and substituted diphenyldiphosphanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0795559-A1 | Substituted diphenylphosphanes and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| EP-0795559-A1 | Substituted diphenylphosphanes and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120122-A1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | CCNH, DBH, FTH1 | TDP1 3670/4885CYP3A4 2788/4885ESR1 2282/4885 |
| US-20010056210-A1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | CCNH, OCIAD2, FTH1 | TDP1 3505/4885CYP3A4 2994/4885ESR1 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.