Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CCR1 | P32246 | 5/20 | 0.60 |
| ▸ | CCR8 | P51685 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724138 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL721902 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1681333 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL8313 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL6513577 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1003398 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL2097101 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL15052618 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL4447950 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL8728454 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628805-B1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL MEDICAL INSTR AG (CH) | 1996-09-18 | — | — | EP | claimed |
| US-5464587-A | In blood | AVL MEDICAL INSTRUMENTS AG (CH) | 1995-11-07 | — | — | US | claimed |
| EP-0628805-A1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL Medical Instruments AG (CH) | 1994-12-14 | — | — | EP | claimed |
| US-6525200-B1 | Fused pyridine and cyclohexane rings and having optionally other substituents; complexing and quantitating such as urea or guanidine | ROCHE DIAGNOSTICS CORPORATION | 2003-02-25 | — | — | US | disclosed |
| EP-0628805-B1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL MEDICAL INSTR AG (CH) | 1996-09-18 | — | — | EP | disclosed |
| US-5464587-A | In blood | AVL MEDICAL INSTRUMENTS AG (CH) | 1995-11-07 | — | — | US | disclosed |
| EP-0628805-A1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL Medical Instruments AG (CH) | 1994-12-14 | — | — | EP | disclosed |