Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882826 | 0.91 | PTGES (0.43) | FFAR4FFAR1PTGESRXRARXRB | |
| SCHEMBL3882264 | 0.88 | THRA (0.51) | FFAR4FFAR1THRATHRB | |
| SCHEMBL3893502 | 0.86 | FFAR4 (0.41) | FFAR4FFAR1PTGESTHRATHRB | |
| SCHEMBL3893496 | 0.86 | FFAR4 (0.41) | FFAR4FFAR1PTGESTHRATHRB | |
| SCHEMBL3885770 | 0.86 | PTGES (0.43) | FFAR4FFAR1PTGESRXRARXRB | |
| SCHEMBL3881786 | 0.85 | FFAR1 (0.52) | FFAR4FFAR1THRATHRBRXRA | |
| SCHEMBL3885360 | 0.84 | AKR1C3 (0.43) | FFAR4FFAR1PPARGPPARDPPARA | |
| SCHEMBL3682378 | 0.81 | CCNC (0.47) | PTGESTHRATHRBPTPN1 | |
| SCHEMBL27627155 | 0.81 | PTGES (0.38) | FFAR4FFAR1PTGESTHRATHRB | |
| SCHEMBL3885728 | 0.81 | FFAR1 (0.48) | FFAR4FFAR1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |