Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879782 | 0.85 | DHODH (0.67) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3673039 | 0.80 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3882170 | 0.79 | RXFP1 (0.52) | SMN1; SMN2LMNAHTTKDM4ERXFP1 | |
| SCHEMBL14396382 | 0.78 | DHODH (0.59) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL11666431 | 0.77 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL11666432 | 0.75 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3881232 | 0.73 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL19376825 | 0.71 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL19376876 | 0.71 | RAF1 (0.61) | RAB9ANPC1SMN1; SMN2NPSR1LMNA | |
| Leflunomide SCHEMBL1243495 | 0.71 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | claimed |
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | disclosed |