Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.44 |
| ▸ | KDM6B | O15054 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608339 | 0.83 | KDM4C (0.45) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL30465694 | 0.83 | KDM4C (0.51) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL123203 | 0.83 | KDM4C (0.51) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL9694347 | 0.81 | ALDH1A1 (0.43) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| Acetic Acid SCHEMBL16666943 | 0.80 | KDM4C (0.49) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL258369 | 0.78 | KDM4C (0.51) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| Hydrochloric Acid SCHEMBL5739434 | 0.77 | KDM4C (0.50) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL12164265 | 0.76 | KDM4E (0.55) | KDM4ETDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL3880004 | 0.75 | KDM4C (0.50) | KDM4CKDM6BKDM4ETDP1KDM4A | |
| SCHEMBL4005290 | 0.75 | GABRP (0.55) | KDM4CKDM6BKDM4ETDP1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111400-A1 | PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS. | AstraZeneca AB (SE) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008085117-A1 | PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS. | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |