SCHEMBL3886595

SCHEMBL3886595

CCN(O)c1ccc(Cc2ccc(N(O)CC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
TSHR P16473 4/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
MAPK1 P28482 2/20 0.52
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KMT2A Q03164 2/20 0.38
ALDH3A1 P30838 1/20 0.35
ALDH1A3 P47895 1/20 0.35
CNR2 P34972 1/20 0.35
CYP2C9 P11712 2/20 0.34
HTT P42858 2/20 0.34
CYP1A2 P05177 1/20 0.34
LTA4H P09960 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831815 0.78 ALDH1A1 (0.46) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL11692293 0.78 ESR1 (0.47) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL459307 0.76 ALDH1A1 (0.60) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL314578 0.75 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4ESR1KMT2A
SCHEMBL1655689 0.75 ALDH1A1 (0.60) ALDH1A1TSHRCYP3A4TDP1MAPK1
Hydrochloric Acid SCHEMBL7930929 0.73 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4ESR1KMT2A
SCHEMBL12680471 0.73 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1MAPK1
SCHEMBL6841550 0.73 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1MAPK1
Bromide SCHEMBL31286101 0.73 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4ESR1KMT2A
SCHEMBL14830543 0.73 HPGD (0.56) ALDH1A1ESR1ESR2KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309662-B1 TRIARYLMETHANE DYES BASF SE (DE) 2009-01-07 EP claimed
US-6846956-B2 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2005-01-25 US claimed
US-20030181740-A1 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 US claimed
EP-1309662-B1 TRIARYLMETHANE DYES BASF SE (DE) 2009-01-07 EP disclosed
US-6846956-B2 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2005-01-25 US disclosed
US-20030181740-A1 Triarylmethane dyes BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 US disclosed