SCHEMBL459307

SCHEMBL459307

CCN(O)c1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
CYP3A4 P08684 5/20 0.60
TDP1 Q9NUW8 4/20 0.60
TSHR P16473 4/20 0.60
MAPK1 P28482 3/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
PSMD14 O00487 1/20 0.60
RECQL P46063 1/20 0.60
GFER P55789 1/20 0.60
ALOX15 P16050 2/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2C9 P11712 1/20 0.44
PRKCI P41743 1/20 0.39
CYP19A1 P11511 1/20 0.39
ACHE P22303 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL672182 0.90 ALDH1A1 (0.50) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL4193147 0.82 CYP3A4 (0.50) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL2831815 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL11692293 0.78 ESR1 (0.47) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL3886595 0.76 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL33781 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL314578 0.75 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRL3MBTL1TP53
SCHEMBL8467252 0.75 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL21065051 0.74 TSHR (0.61) ALDH1A1CYP3A4TDP1TSHRMAPK1
SCHEMBL10369416 0.74 CYP3A4 (0.42) ALDH1A1CYP3A4TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362893-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, N,N-DICARBOXYMETHYLGLUTAMIC ACID, PROPANE-1,3-DIOL, AT LEAST ONE FATTY SUBSTANCE OTHER THAN FATTY ACIDS, AT LEAST ONE DYE L'OREAL (FR) 2024-05-08 EP claimed
EP-4362891-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2024-05-08 EP claimed
EP-4362889-A1 COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, 1,3-PROPANEDIOL, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2024-05-08 EP claimed
EP-4262716-A1 COMPOSITION COMPRISING A PARTICULAR OXIDATION DYE PRECURSOR AND A PARTICULAR CARBOXYLIC ACID L'OREAL (FR) 2023-10-25 EP claimed
EP-4262723-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND AN ALKYL(POLY)GLYCOSIDE L'OREAL (FR) 2023-10-25 EP claimed
EP-4262724-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PARTICULAR CARBOXYLIC ACID L'OREAL (FR) 2023-10-25 EP claimed
EP-4262721-A1 COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AN OXYETHYLENATED FATTY ACID ESTER OF SORBITAN AND A FATTY ACID L'OREAL (FR) 2023-10-25 EP claimed
EP-4262722-A1 COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PARTICULAR OXYETHYLENATED FATTY ACID ESTER OF SORBITAN L'OREAL (FR) 2023-10-25 EP claimed
EP-4262720-A1 COMPOSITION COMPRISING TWO PARTICULAR OXIDATION DYE PRECURSORS, AND A PARTICULAR CARBOXYLIC ACID L'OREAL (FR) 2023-10-25 EP claimed
WO-2023118332-A1 COMPOSITION COMPRISING TWO POLYOLS DIFFERENT FROM ONE ANOTHER, AN ALKALINE AGENT AND A DYE L'OREAL (FR) 2023-06-29 WO claimed
CN-101848695-A Oxidative hair colorant compositions PROCTER & GAMBLE 2010-09-29 CN claimed
US-7597720-B2 Oxidizing hair colourant compositions THE PROCTER & GAMBLE COMPANY (US) 2009-10-06 US claimed
EP-2103299-A2 Oxidizing hair colourant compositions The Procter and Gamble Company (US) 2009-09-23 EP claimed
US-20090119852-A1 Oxidizing Hair Colourant Compositions WELLA OPERATIONS US, LLC 2009-05-14 US claimed
WO-2009060334-A2 OXIDIZING HAIR COLOURANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2009-05-14 WO claimed
WO-2007097928-A2 HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-08-30 WO claimed
EP-1820488-A2 Hair colouring compositions The Procter and Gamble Company (US) 2007-08-22 EP claimed
US-20070186357-A1 Hair colouring compositions THE PROCTER & GAMBLE COMPANY 2007-08-16 US claimed
US-7033401-B2 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds WELLA AG (DE) 2006-04-25 US claimed
US-4828568-A N-(2,4-DIHYDROXYBENZYLIDENE)AMINO COMPOUNDS AS PRIMARY COUPLERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-05-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090119852-A1 Oxidizing Hair Colourant Compositions TET1, TET2, TET3 ALDH1A1 533/4885CYP3A4 1091/4885TDP1 883/4885
US-20070186357-A1 Hair colouring compositions COX5A, COXFA4L2, COX5B ALDH1A1 386/4885CYP3A4 2585/4885TDP1 1612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.