Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883120 | 0.99 | BRD4 (0.42) | BRD4HPGDSPTGER1PTGER4PTGER3 | |
| SCHEMBL3896075 | 0.88 | KDM4E (0.39) | BRD4HPGDSKDM4EAPAF1POLB | |
| SCHEMBL3883911 | 0.87 | KDM4E (0.40) | BRD4KDM4EAPAF1POLBMAPT | |
| SCHEMBL3881280 | 0.84 | THRA (0.45) | BRD4HPGDSPTGER1ADRB3HTR1A | |
| SCHEMBL3884976 | 0.84 | PPARG (0.40) | BRD4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3686227 | 0.83 | THRA (0.43) | BRD4HPGDSPTGER1 | |
| SCHEMBL3886710 | 0.82 | BRD4 (0.42) | BRD4HPGDSPTGER1ADRB3ADRB2 | |
| SCHEMBL3884668 | 0.82 | PTGS2 (0.42) | PTGER1PTGER4PTGER3PTGER2SRC | |
| SCHEMBL3685940 | 0.81 | BRD4 (0.42) | BRD4HPGDSPTGER1HTR1A | |
| SCHEMBL3888826 | 0.80 | PTGER1 (0.39) | BRD4PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |