Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 3/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884531 | 0.91 | MAP4K4 (0.36) | XDHKMOP2RX3 | |
| SCHEMBL3680931 | 0.86 | S1PR1 (0.49) | PDE4BXDHNPC1RAB9A | |
| SCHEMBL3882568 | 0.83 | MDM2 (0.38) | XDHP2RX3KEAP1NFE2L2 | |
| SCHEMBL3884291 | 0.83 | CYP1A2 (0.40) | XDHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3888367 | 0.83 | PDE4B (0.44) | PDE4BXDHKEAP1NFE2L2HCRTR1 | |
| SCHEMBL3691485 | 0.83 | S1PR1 (0.41) | PDE4BXDHLIPGHCRTR1HCRTR2 | |
| SCHEMBL3882409 | 0.81 | PTGER1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL3890246 | 0.80 | PTGER1 (0.40) | XDHP2RX3KEAP1NFE2L2 | |
| SCHEMBL3893373 | 0.80 | AKR1C3 (0.43) | XDHKEAP1NFE2L2 | |
| SCHEMBL3887479 | 0.80 | HPGD (0.44) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |