Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880637 | 0.89 | C5AR1 (0.43) | AKR1C3AKR1C2PPARGXDHC5AR1 | |
| SCHEMBL3889875 | 0.88 | AKR1C3 (0.43) | AKR1C3AKR1C2XDHC5AR1PTGER1 | |
| SCHEMBL3882409 | 0.87 | PTGER1 (0.42) | AKR1C3AKR1C2PPARGC5AR1PTGER1 | |
| SCHEMBL3882883 | 0.85 | THRA (0.47) | PPARGXDHFFAR4C5AR1GSK3B | |
| SCHEMBL3881996 | 0.84 | KEAP1 (0.40) | PPARGXDHC5AR1PTGER1PTGER4 | |
| SCHEMBL3884007 | 0.83 | PTGER1 (0.39) | C5AR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3890246 | 0.83 | PTGER1 (0.40) | PPARGXDHC5AR1PTGER1PTGER4 | |
| SCHEMBL3893376 | 0.82 | PPARG (0.41) | PPARGXDHFFAR4C5AR1GSK3B | |
| SCHEMBL3882520 | 0.82 | KEAP1 (0.38) | PPARGXDHC5AR1PTGER1PTGER4 | |
| SCHEMBL3884291 | 0.82 | CYP1A2 (0.40) | XDHC5AR1SRCYES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |