SCHEMBL3887308

SCHEMBL3887308

C[Si](C)(CCCCO)N[Si](C)(C)CCCCO

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.35
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1710535 0.73
SCHEMBL8453582 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL20895866 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL2305409 0.71
SCHEMBL3824548 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1710256 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL2331806 0.71 TSHR (0.35) LMNAALDH1A1TSHR
SCHEMBL12134329 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1710307 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL12134313 0.71 LMNA (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed