⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506993 | 0.80 | — | — | |
| SCHEMBL6265139 | 0.73 | — | — | |
| SCHEMBL758808 | 0.71 | — | — | |
| SCHEMBL771952 | 0.71 | — | — | |
| SCHEMBL5652197 | 0.69 | — | — | |
| SCHEMBL12806345 | 0.69 | ADH1B (0.35) | — | |
| SCHEMBL8629305 | 0.65 | ADH1B (0.38) | — | |
| SCHEMBL9820305 | 0.61 | — | — | |
| SCHEMBL6265134 | 0.61 | ADH1B (0.33) | — | |
| SCHEMBL6740966 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969268-B1 | METHOD FOR PRODUCING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2023-07-05 | — | — | EP | claimed |
| EP-3976362-B1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-06-07 | — | — | EP | claimed |
| US-20220296610-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFECTION AND NOVEL COSMECEUTICAL PREPARATIONS | DERM BIOME PHARMACEUTICALS INC (CA) | 2022-09-22 | — | — | US | disclosed |
| WO-2021006182-A1 | LIQUID CRYSTAL-ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | 日産化学株式会社 | 2021-01-14 | — | — | WO | disclosed |
| US-20160317672-A1 | DERIVATIVE OF STYRENE-MALEIC ACID COPOLYMER | Maeda, Hiroshi (JP) | 2016-11-03 | — | — | US | disclosed |
| US-9162986-B2 | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | PHARMACYCLICS LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140378453-A1 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | PHARMACYCLICS LLC | 2014-12-25 | — | — | US | disclosed |
| US-8778625-B2 | 2-(2-hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | PHARMACYCLICS, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8475768-B2 | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2013-07-02 | — | — | US | disclosed |
| US-8475768-B2 | Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) | GE HEALTHCARE AS (NO) | 2013-07-02 | — | — | US | disclosed |
| US-8299110-B2 | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors | PHARMACYCLICS, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| US-7943616-B2 | Protein kinase inhibitors; astham; psoriasis; antiinflammatory agents; inflammatory bowel disorders | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110110865-A1 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-05-12 | — | — | US | disclosed |
| US-20110110865-A1 | CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2011-05-12 | — | — | US | disclosed |
| EP-2298782-A1 | Method for producing pyrazole glycoside derivatives | Sanofi-Aventis (FR) | 2011-03-23 | — | — | EP | disclosed |
| US-20090054432-A1 | 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors | PHARMACYLICS, INC. A DELAWARE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2009021948-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021947-A1 | CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) | GE HEALTHCARE AS (NO) | 2009-02-19 | — | — | WO | disclosed |
| US-7479502-B2 | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | PHARMACYCLICS, INC. (US) | 2009-01-20 | — | — | US | disclosed |
| EP-1594885-B1 | MEDICAMENT FOR INHIBITING TUMOUR GROWTH | NOVELIX PHARMACEUTICALS INC (US) | 2009-01-07 | — | — | EP | disclosed |