Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.49 |
| ▸ | GALR2 | O43603 | 4/20 | 0.40 |
| ▸ | GALR1 | P47211 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878640 | 0.89 | GALR2 (0.43) | GALR2GALR1 | |
| SCHEMBL3884829 | 0.86 | TRPV1 (0.46) | TRPV1GALR2GALR1 | |
| SCHEMBL3882315 | 0.85 | GALR2 (0.43) | GALR2GALR1 | |
| SCHEMBL13761418 | 0.85 | GALR2 (0.42) | GALR2GALR1 | |
| SCHEMBL3877789 | 0.84 | TRPV1 (0.46) | TRPV1GALR2GALR1 | |
| SCHEMBL3888307 | 0.83 | GALR2 (0.41) | TRPV1GALR2GALR1 | |
| SCHEMBL13761493 | 0.82 | GALR2 (0.40) | TRPV1GALR2GALR1 | |
| SCHEMBL3882111 | 0.82 | GALR2 (0.40) | GALR2GALR1 | |
| SCHEMBL3948366 | 0.82 | HSD11B1 (0.43) | GALR2GALR1 | |
| SCHEMBL3876034 | 0.82 | TRPV1 (0.44) | TRPV1GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |