Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.50 |
| ▸ | CDK4 | P11802 | 6/20 | 0.47 |
| ▸ | CCND1 | P24385 | 6/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892910 | 0.87 | IMPDH2 (0.53) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL3951987 | 0.79 | HPGD (0.55) | CHEK1CDK4CCND1GABRPGABRD | |
| SCHEMBL3876965 | 0.76 | IMPDH2 (0.55) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL28182943 | 0.76 | IMPDH2 (0.55) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL5830117 | 0.76 | CHEK1 (0.56) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL4901329 | 0.76 | IMPDH2 (0.55) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL14198729 | 0.76 | MEN1 (0.73) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL348241 | 0.75 | CDK4 (0.58) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL27048149 | 0.75 | CHEK1 (0.55) | IMPDH2IMPDH1CHEK1CDK4CCND1 | |
| SCHEMBL38828 | 0.74 | KIF11 (0.57) | CDK4CCND1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362463-B2 | Organometallic complexes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-20 | — | — | US | disclosed |
| EP-1859656-A2 | ORGANOMETALLIC COMPLEXES | E.I. du Pont de Nemours and Company (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006072002-A2 | ORGANOMETALLIC COMPLEXES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090206327-A1 | ORGANOMETALLIC COMPLEXES | SLC25A11, TIMM9, TIMM50 | IMPDH2 2778/4885IMPDH1 3080/4885CHEK1 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.