SCHEMBL3889262

SCHEMBL3889262

c1ccc(Sc2ccc(Sc3cccc(Sc4ccccc4)c3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
MAOB P27338 3/20 0.56
HTR2C P28335 2/20 0.54
HTR6 P50406 1/20 0.54
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
SLC6A4 P31645 1/20 0.48
HPGD P15428 2/20 0.48
ALDH1A1 P00352 2/20 0.48
ANXA2 P07355 1/20 0.45
S100A10 P60903 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MGLL Q99685 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
MAPK1 P28482 2/20 0.41
NR1H2 P55055 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3904216 1.00 MAOA (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3903397 1.00 MAOA (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3903581 1.00 MAOA (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3902722 1.00 MAOA (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL9557022 0.97 HTR2C (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3894071 0.97 HTR2C (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3889754 0.97 HTR2C (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL3893269 0.97 HTR2C (0.56) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL4869740 0.90 MAOA (0.48) MAOAMAOBHTR2CHTR6BCL2
SCHEMBL6947110 0.88 MAOA (0.50) MAOAMAOBHTR2CHTR6BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468229-B2 Polyphenyl thioether and thiophosphate containing photoconductors XEROX CORPORATION (US) 2008-12-23 US claimed
US-7462432-B2 Extended lifetimes of service in excess of about 3,500,000 imaging cycles; excellent electronic characteristics; stable electrical properties; low image ghosting; resistance to charge transport layer cracking upon exposure to the vapor of certain solvents; surface characteristics, wear resistance XEROX CORPORATION (US) 2008-12-09 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292790-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US disclosed
US-7507510-B2 Polyphenyl ether phosphate containing photoconductors XEROX CORPORATION (US) 2009-03-24 US disclosed
US-7498108-B2 Thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-03-03 US disclosed
US-7491480-B2 Thiophosphate and antioxidant containing photoconductors XEROX CORPORATION (US) 2009-02-17 US disclosed
US-7479358-B2 Ether and thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-01-20 US disclosed
US-7476478-B2 Polyphenyl thioether and antioxidant containing photoconductors XEROX CORPORATION (US) 2009-01-13 US disclosed
US-7476477-B2 Thiophosphate containing photoconductors XEROX CORPORATION (US) 2009-01-13 US disclosed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-20070026233-A1 Photoreceptor layer having polyether lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed
EP-0279217-B1 PROCESS FOR THE PREPARATION OF POLY(ARYLENSULFIDES) WITH ADJUSTABLE MELT VISCOSITY BAYER AG (DE) 1992-03-11 EP disclosed
US-4046749-A Phenylene sulfide oligomer production PHILLIPS PETROLEUM COMPANY (US) 1977-09-06 US disclosed