Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.76 |
| ▸ | CA9 | Q16790 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | AURKA | O14965 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889647 | 1.00 | FAAH (0.76) | FAAHCA9LMNAAURKATDP1 | |
| SCHEMBL17302231 | 0.92 | FAAH (0.89) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL11319299 | 0.90 | FAAH (0.84) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL17302141 | 0.90 | FAAH (0.84) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL3901529 | 0.89 | AURKA (0.72) | FAAHCA9LMNAAURKATDP1 | |
| SCHEMBL3901533 | 0.89 | AURKA (0.72) | FAAHCA9LMNAAURKATDP1 | |
| SCHEMBL17295325 | 0.88 | FAAH (0.84) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL17302128 | 0.88 | FAAH (0.89) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL17295326 | 0.88 | FAAH (0.84) | FAAHCA9LMNAS1PR1S1PR3 | |
| SCHEMBL3887237 | 0.88 | FAAH (0.80) | FAAHCA9LMNAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |