Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659778 | 0.85 | POLB (0.46) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3884033 | 0.77 | HTT (0.39) | HTTCYP2C19ALDH1A1MAPTNPSR1 | |
| SCHEMBL9638444 | 0.76 | CYP2C9 (0.40) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8848320 | 0.75 | BLM (0.38) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10455020 | 0.75 | KDM4E (0.47) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10455022 | 0.75 | KDM4E (0.47) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1747654 | 0.74 | HTT (0.72) | HTTHSD17B10ALDH1A1MAPTNPSR1 | |
| SCHEMBL4804696 | 0.74 | BLM (0.44) | CYP2C9CYP2C19ALDH1A1ESR1ESR2 | |
| SCHEMBL11003311 | 0.72 | CYP2C9 (0.44) | HTTHSD17B10CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8037706 | 0.71 | ALDH1A1 (0.45) | HTTCYP2C9CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264660-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | Kang, Heonjoong (KR) | 2009-10-22 | — | — | US | claimed |
| EP-1812386-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | Kang, Heonjoong (KR) | 2007-08-01 | — | — | EP | claimed |
| WO-2006043797-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | KANG HEONJOONG (KR) | 2006-04-27 | — | — | WO | claimed |
| US-20090264660-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | Kang, Heonjoong (KR) | 2009-10-22 | — | — | US | disclosed |
| EP-1812386-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | Kang, Heonjoong (KR) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006043797-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | KANG HEONJOONG (KR) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264660-A1 | PROCESS FOR ALKYL ARYL SULFIDE DERIVATIVES AND NEW SULFIDE COMPOUNDS | TST, ARSA, STS | HTT 2818/4885HSD17B10 545/4885CYP2C9 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.