SCHEMBL499558

SCHEMBL499558

CCn1n[c]nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7287279 0.74 TBXAS1 (0.31)
SCHEMBL2105621 0.72
SCHEMBL2994320 0.65
SCHEMBL8848238 0.65 ALDH1A1 (0.33)
SCHEMBL333208 0.64
SCHEMBL3733743 0.62 LTA4H (0.34)
SCHEMBL38918 0.61
SCHEMBL8791559 0.57
SCHEMBL9114146 0.39
SCHEMBL179702 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107118170-B Preparation method of azoxytetrazole 北京理工大学 2020-01-07 CN claimed
US-9018175-B2 3,4,4a,10b-Tetrahydro-1H-thiopyrano-[44,3-c] isoquinoline derivatives TAKEDA GMBH (DE) 2015-04-28 US claimed
EP-2513119-B1 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4,3-C]ISOQUINOLINE DERIVATIVES TAKEDA GMBH (DE) 2014-06-25 EP claimed
US-20120289474-A1 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4,3-c] ISOQUINOLINE DERIVATIVES NYCOMED GMBH (DE) 2012-11-15 US claimed
EP-2513119-A1 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c]ISOQUINOLINE DERIVATIVES Nycomed GmbH (DE) 2012-10-24 EP claimed
US-8119563-B2 N-substituted azacycles FMC CORPORATION (US) 2012-02-21 US claimed
WO-2011073231-A1 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4, 3-c] ISOQUINOLINE DERIVATIVES NYCOMED GMBH (DE) 2011-06-23 WO claimed
US-20090227555-A2 Novel Pyridine Compounds ASTRAZENECA AB (SE) 2009-09-10 US claimed
US-20090215821-A1 N-Substituted Azacycles FMC CORPORATION 2009-08-27 US claimed
US-7501445-B2 Imidazolidinone compounds NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2009-03-10 US claimed
EP-0971901-B1 PHTHALAZINONES ALTANA PHARMA AG (DE) 2003-02-26 EP claimed
WO-2002022630-A1 PURINE DERIVATIVES PFIZER LIMITED (GB) 2002-03-21 WO claimed
US-H1996-H1 AGRICULTURE FMC CORPORATION 2001-10-02 US claimed
US-6103718-A Phthalazinones BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-08-15 US claimed
WO-2000031034-A1 INSECTICIDAL PHOTOSTABLE ACID SALT DERIVATIVES OF N-BENZYL-4-BENZHYDROLPIPERIDINES FMC CORPORATION (US) 2000-06-02 WO claimed
US-H1838-H MITICIDES FMC CORPORATION 2000-02-01 US claimed
EP-0971901-A1 PHTHALAZINONES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2000-01-19 EP claimed
WO-1998031674-A1 PHTHALAZINONES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-07-23 WO claimed
US-5217975-A AZABICYCLIC COMPOUNDS FOR TREATING DEMENTIA BEECHAM GROUP P.L.C. (GB) 1993-06-08 US claimed
EP-0402056-A2 Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them Beecham Group p.l.c. (GB) 1990-12-12 EP claimed