Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | GLI2 | P10070 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892615 | 1.00 | FFAR1 (0.42) | FFAR1PTGS2METENPP2CTSK | |
| SCHEMBL3886545 | 0.93 | PTGS2 (0.40) | FFAR1PTGS2METENPP2CTSK | |
| SCHEMBL3895740 | 0.89 | PTGS2 (0.43) | PTGS2METENPP2CTSKCTSS | |
| SCHEMBL3885022 | 0.87 | FFAR1 (0.49) | FFAR1FFAR4FBP1 | |
| SCHEMBL3882120 | 0.86 | FFAR1 (0.45) | FFAR1PTGS2METENPP2CTSK | |
| SCHEMBL3893121 | 0.82 | FFAR1 (0.41) | FFAR1FFAR4 | |
| SCHEMBL3893124 | 0.82 | FFAR1 (0.41) | FFAR1FFAR4 | |
| SCHEMBL3880630 | 0.82 | FFAR1 (0.49) | FFAR1PTGS2METENPP2CTSK | |
| SCHEMBL3887997 | 0.82 | THRA (0.46) | PTGS2ENPP2FFAR4F7F3 | |
| SCHEMBL3888001 | 0.82 | THRA (0.46) | PTGS2ENPP2FFAR4F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |