Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 8/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.32 |
| ▸ | PADI3 | Q9ULW8 | 6/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892003 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9PADI1 | |
| SCHEMBL11996382 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996383 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996381 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3887727 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996376 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996378 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL11996377 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3896531 | 0.78 | PTGES (0.46) | ALDH1A1MEN1KMT2ACA9MAPT | |
| SCHEMBL3896527 | 0.78 | PTGES (0.46) | ALDH1A1MEN1KMT2ACA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |