Acifluorfen

Acifluorfen

SCHEMBL38929

O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 1/20 1.00
TTR P02766 1/20 1.00
PPOX P50336 1/20 1.00
KMT2A Q03164 1/20 1.00
FFAR1 O14842 5/20 0.53
PYGL P06737 1/20 0.50
AKR1B1 P15121 1/20 0.50
AKR1C4 P17516 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50
MRGPRX4 Q96LA9 5/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
CCR6 P51684 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL29448829 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL3228873 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8028079 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL29445767 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL1830812 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL10556004 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL3690938 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL10542053 0.96 TDP1 (0.92) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8936622 0.95 TDP1 (0.90) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8028082 0.95 TDP1 (0.90) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22623 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144260-A1 COMPOSITION AND METHOD FOR IMPROVING AGRONOMIC TRAITS OF A PLANT THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-05-28 US claimed
CN-109476709-B Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variants thereof FARMHANNONG Co.,Ltd. (KR) 2026-05-26 CN claimed
CN-118266468-B Weeding composition containing protoporphyrinogen oxidase inhibitor and application thereof 青岛恒宁生物科技有限公司 2026-05-15 CN claimed
US-20260120816-A1 PREDICTION METHOD FOR PROTOPORPHYRINOGEN OXIDASE (PPO) INHIBITOR PAN ADVANCED BUSINESS RESEARCH, LLC (JP) 2026-04-30 US claimed
US-20260101896-A1 AQUEOUS HERBICIDAL CONCENTRATES MONSANTO TECHNOLOGY LLC (US) 2026-04-16 US claimed
US-20260096553-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2026-04-09 US claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
WO-2026042054-A1 HERBICIDAL COMBINATIONS UPL MAURITIUS LIMITED (MU) 2026-02-26 WO claimed
US-12550896-B2 Early applications of encapsulated acetamides for reduced injury in crops MONSANTO TECHNOLOGY LLC (US) 2026-02-17 US claimed
EP-0113857-A1 Herbicidal agents BAYER AG (DE) 1984-07-25 EP claimed
US-4455437-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1984-06-19 US claimed
US-4448982-A Selective process for the preparation of hydroxy alkyl phenoxy benzoates GAF CORPORATION (US) 1984-05-15 US claimed
US-4424393-A Process of preparation of substituted diphenyl ethers PPG INDUSTRIES, INC. (US) 1984-01-03 US claimed
US-4405805-A ACIFLUORFEN, XYLENE EXTRACTION RHONE-POULENC, INC. (US) 1983-09-20 US claimed
US-4395570-A CONDENSATION OF 4-TRIFLUOROMETHYLPHENOL WITH 1-HAL-4-SUBSTITUTED-4-NITROBENZENE, THEN HALOGENATION ROHM AND HAAS COMPANY (US) 1983-07-26 US claimed
EP-0080312-A1 The preparation of certain diphenyl ethers especially 5-(4-trifluoromethylphenoxy)- and 5-(2-halo-4-trifluoromethylphenoxy)-2-nitrobenzoic acid and salts and esters and amides ROHM AND HAAS COMPANY (US) 1983-06-01 EP claimed
EP-0013660-B1 AMINOALKYL ESTERS OF 2-NITRO-5-(ORTHO-CHLORO-PARA-TRIFLUOROMETHYLPHENOXY)-BENZOIC ACID, THEIR PREPARATION, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND THEIR USE CIBA-GEIGY AG (CH) 1983-05-18 EP claimed
EP-0044209-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-20 EP claimed
EP-0013660-A1 Aminoalkyl esters of 2-nitro-5-(ortho-chloro-para-trifluoromethylphenoxy)-benzoic acid, their preparation, herbicides containing them as active ingredients, and their use CIBA-GEIGY AG (CH) 1980-07-23 EP claimed