Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058466 | 0.94 | SLC6A5 (0.58) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL2403510 | 0.92 | SLC6A5 (0.55) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL16799424 | 0.90 | SLC6A5 (0.53) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL16799036 | 0.90 | SLC6A5 (0.53) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL9508493 | 0.90 | SLC6A5 (0.53) | SLC6A5PAOXKDM4AHIF1ATET2 | |
| SCHEMBL16798900 | 0.90 | SLC6A5 (0.53) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL9505937 | 0.88 | SLC6A5 (0.46) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL8863653 | 0.88 | SLC6A5 (0.50) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL7215984 | 0.88 | SLC6A5 (0.67) | SLC6A5PAOXFAAHKDM4AHIF1A | |
| SCHEMBL7215946 | 0.88 | SLC6A5 (0.67) | SLC6A5PAOXFAAHKDM4AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842196-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2007-11-21 | — | — | EP | claimed |
| US-6875743-B1 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2005-04-05 | — | — | US | claimed |
| US-6596687-B1 | For treatment of many inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-07-22 | — | — | US | claimed |
| US-6239108-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2001-05-29 | — | — | US | claimed |
| EP-0842196-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1998-05-20 | — | — | EP | claimed |
| WO-1997003094-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-01-30 | — | — | WO | claimed |
| EP-1778717-A4 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2009-01-21 | — | — | EP | disclosed |
| EP-0842196-B1 | CELL ADHESION INHIBITORS | BIOGEN IDEC INC (US) | 2007-11-21 | — | — | EP | disclosed |
| EP-1778717-A2 | CELL ADHESION INHIBITORS | Biogen Idec MA, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7196112-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-20070066533-A1 | Cell adhesion inhibitors | LEE WEN-CHERNG | 2007-03-22 | — | — | US | disclosed |
| WO-2006019632-A2 | CELL ADHESION INHIBITORS | BIOGEN IDEC MA INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060014966-A1 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. | 2006-01-19 | — | — | US | disclosed |
| US-6875743-B1 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2005-04-05 | — | — | US | disclosed |
| US-6596687-B1 | For treatment of many inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-07-22 | — | — | US | disclosed |
| US-6248713-B1 | OLIGOPEPTIDE FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | BIOGEN, INC. | 2001-06-19 | — | — | US | disclosed |
| US-6239108-B1 | Cell adhesion inhibitors | BIOGEN, INC. | 2001-05-29 | — | — | US | disclosed |
| WO-1997003094-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066533-A1 | Cell adhesion inhibitors | VCAM1, EPCAM, ICAM1 | SLC6A5 3228/4885PAOX 3736/4885FAAH 2388/4885 |
| US-20060014966-A1 | Cell adhesion inhibitors | VCAM1, EPCAM, ICAM1 | SLC6A5 3228/4885PAOX 3736/4885FAAH 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.