⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897004 | 1.00 | — | — | |
| SCHEMBL3882363 | 0.85 | LMNA (0.30) | — | |
| SCHEMBL3886396 | 0.85 | LMNA (0.30) | — | |
| SCHEMBL3896608 | 0.82 | — | — | |
| SCHEMBL3896117 | 0.82 | — | — | |
| SCHEMBL3887951 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL5006776 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL3883044 | 0.80 | — | — | |
| SCHEMBL3897002 | 0.80 | — | — | |
| SCHEMBL1891009 | 0.79 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566738-B2 | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use | XENOPORT, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080242723-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS OF SULFINIC ACIDS, METHODS OF SYNTHESIS, AND USE | XENOPORT, INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20060111439-A1 | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use | XENOPORT, INC. | 2006-05-25 | — | — | US | disclosed |