Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285815 | 0.76 | ALDH1A1 (0.50) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| SCHEMBL15575123 | 0.75 | PDE3B (0.33) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL5908134 | 0.72 | MEN1 (0.41) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| Pyrrole SCHEMBL28193076 | 0.69 | ALDH1A1 (0.47) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| SCHEMBL4511175 | 0.67 | NISCH (0.39) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| Isoxazole SCHEMBL28776356 | 0.66 | MEN1 (0.44) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| SCHEMBL81650 | 0.60 | NISCH (0.59) | MEN1ALDH1A1KMT2ANISCHMTOR | |
| SCHEMBL100765 | 0.60 | HPGDS (0.46) | ADRA1DADRA1A | |
| SCHEMBL21104225 | 0.59 | HPGDS (0.33) | — | |
| SCHEMBL28425230 | 0.58 | NISCH (0.56) | MEN1ALDH1A1KMT2ANISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651167-A4 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A PDE-4 INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | EPIGENESIS PHARMACEUTICALS LLC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1651167-A2 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A PDE-4 INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | Epigenesis Pharmaceuticals LLC (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005011602-A2 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A PDE-4 INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE | EPIGENESIS PHARMACEUTICALS LLC (US) | 2005-02-10 | — | — | WO | disclosed |