Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892980 | 0.92 | ALDH1A1 (0.63) | ALDH1A1POLBCHRNA7MMP13MEN1 | |
| SCHEMBL3901126 | 0.91 | ALDH1A1 (0.67) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL3900093 | 0.90 | ALDH1A1 (0.66) | ALDH1A1POLBCHRNA7 | |
| SCHEMBL3906914 | 0.88 | ALDH1A1 (0.63) | ALDH1A1POLBCHRNA7HTR3A | |
| SCHEMBL3892933 | 0.86 | ALDH1A1 (0.89) | ALDH1A1POLBCHRNA7MEN1KMT2A | |
| SCHEMBL7060582 | 0.86 | ALDH1A1 (0.72) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL7060957 | 0.85 | ALDH1A1 (0.70) | ALDH1A1POLBCHRNA7MEN1KMT2A | |
| SCHEMBL7128710 | 0.85 | ALDH1A1 (0.73) | ALDH1A1POLBCHRNA7MMP13HTR3A | |
| SCHEMBL4198287 | 0.85 | ALDH1A1 (0.59) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL4198282 | 0.85 | ALDH1A1 (0.59) | ALDH1A1POLBCHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | claimed |