Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.89 |
| ▸ | POLB | P06746 | 3/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062806 | 0.94 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMAPTMEN1 | |
| SCHEMBL3898882 | 0.94 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMAPTMEN1 | |
| SCHEMBL3905397 | 0.93 | ALDH1A1 (0.85) | ALDH1A1POLBKMT2AMAPTMEN1 | |
| SCHEMBL3901126 | 0.87 | ALDH1A1 (0.67) | ALDH1A1POLBMAPTCHRNA7LMNA | |
| SCHEMBL3896701 | 0.86 | ALDH1A1 (0.66) | ALDH1A1POLBKMT2AMEN1CHRNA7 | |
| SCHEMBL3900093 | 0.86 | ALDH1A1 (0.66) | ALDH1A1POLBCHRNA7 | |
| SCHEMBL7057984 | 0.85 | ALDH1A1 (0.81) | ALDH1A1POLBKMT2AMAPTMEN1 | |
| SCHEMBL3906914 | 0.83 | ALDH1A1 (0.63) | ALDH1A1POLBCHRNA7 | |
| SCHEMBL4205819 | 0.83 | ALDH1A1 (0.78) | ALDH1A1POLBKMT2AMAPTMEN1 | |
| SCHEMBL4201218 | 0.83 | ALDH1A1 (0.78) | ALDH1A1POLBKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | claimed |
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | disclosed |