Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 18/20 | 0.44 |
| ▸ | NMBR | P28336 | 2/20 | 0.39 |
| ▸ | GRPR | P30550 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897017 | 1.00 | KCNA3 (0.44) | KCNA3NMBRGRPR | |
| SCHEMBL3895390 | 0.83 | KCNA3 (0.66) | KCNA3 | |
| SCHEMBL7246303 | 0.80 | HTR2A (0.38) | — | |
| SCHEMBL3898023 | 0.80 | HTR2A (0.38) | — | |
| SCHEMBL3896518 | 0.78 | KCNA3 (0.52) | KCNA3 | |
| SCHEMBL18542634 | 0.75 | MGLL (0.50) | — | |
| SCHEMBL3908651 | 0.75 | KCNA3 (0.47) | KCNA3 | |
| SCHEMBL3900137 | 0.75 | KCNA3 (0.47) | KCNA3 | |
| SCHEMBL3900140 | 0.75 | KCNA3 (0.47) | KCNA3 | |
| SCHEMBL3967950 | 0.75 | HTT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143965-B1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-02-25 | — | — | EP | disclosed |
| US-6632836-B1 | To treat autoimmune disorders, cardiac arrhythmias and the like | MERCK & CO., INC. | 2003-10-14 | — | — | US | disclosed |
| US-6599902-B2 | For treating or preventing a protein kinase related disorder | SUGEN, INC. | 2003-07-29 | — | — | US | disclosed |