Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898023 | 1.00 | HTR2A (0.38) | HTR2ASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL3897014 | 0.81 | ALDH1A1 (0.36) | HTR2ASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL3897013 | 0.80 | KCNA3 (0.44) | — | |
| SCHEMBL3897017 | 0.80 | KCNA3 (0.44) | — | |
| SCHEMBL7249217 | 0.77 | MEN1 (0.44) | SMN1; SMN2ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL7243316 | 0.74 | SLC6A4 (0.39) | — | |
| SCHEMBL3901076 | 0.74 | SLC6A4 (0.39) | — | |
| SCHEMBL20625250 | 0.73 | GAA (0.51) | HTR2ASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL2803619 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTMGLLLMNA | |
| SCHEMBL2722317 | 0.70 | CYP1A2 (0.49) | HTR2ASMN1; SMN2ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632836-B1 | To treat autoimmune disorders, cardiac arrhythmias and the like | MERCK & CO., INC. | 2003-10-14 | — | — | US | disclosed |