Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200253 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7516424 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7513498 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL608444 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11136407 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL942766 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3180403 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL10758355 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL16335520 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7519180 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448673-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS | BAUSCH & LOMB (US) | 2009-02-11 | — | — | EP | disclosed |
| US-7132492-B2 | High refractive index aromatic-based prepolymer precursors | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-7132493-B2 | High refractive index aromatic-based prepolymer precursors | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-7098288-B2 | High refractive index aromatic-based prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2006-08-29 | — | — | US | disclosed |
| US-7074873-B2 | High refractive index aromatic-based prepolymers | RAUSCH & LOMB INCORPORATED (US) | 2006-07-11 | — | — | US | disclosed |
| US-6951914-B2 | High refractive index aromatic-based prepolymer precursors | BAUSCH & LOMB INCORPORATED (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050171314-A1 | High refractive index aromatic-based prepolymers | LAI YU-CHIN (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050165246-A1 | High refractive index aromatic-based prepolymer precursors | LAI YU-CHIN (US) | 2005-07-28 | — | — | US | disclosed |
| US-20050128425-A1 | High refractive index aromatic-based prepolymers | SALIX PHARMACEUTICALS, LTD. | 2005-06-16 | — | — | US | disclosed |
| US-6864342-B2 | High refractive index aromatic-based prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2005-03-08 | — | — | US | disclosed |
| EP-1448673-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS | Bausch & Lomb Incorporated (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6777522-B2 | COPOLYMERIZATION OF ONE OR MORE AROMATIC-SUBSTITUTED POLYSILOXANE PREPOLYMERS WITH ONE OR MORE UNSATURATED MONOMERS, ESPECIALLY ACRYLIC MONOMERS; INTRAOCULAR LENSES AND CORNEAL INLAYS | BAUSCH & LOMB INCORPORATED | 2004-08-17 | — | — | US | disclosed |
| US-20040155373-A1 | High refractive index aromatic-based prepolymer precursors | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2004-08-12 | — | — | US | disclosed |
| US-20040158020-A1 | High refractive index aromatic-based prepolymer precursors | SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) | 2004-08-12 | — | — | US | disclosed |
| US-20040158019-A1 | High refractive index aromatic-based prepolymer precursors | LAI YU-CHIN (US) | 2004-08-12 | — | — | US | disclosed |
| EP-1444275-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20030134977-A1 | High refractive index aromatic-based prepolymers | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2003-07-17 | — | — | US | disclosed |
| US-20030130465-A1 | High refractive index aromatic-based prepolymer precursors | BAUSCH HEALTH IRELAND LIMITED (F/K/A/ VALEANT PHARMACEUTICALS IRELAND LIMITED) (IE) | 2003-07-10 | — | — | US | disclosed |
| WO-2003040200-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040214-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134977-A1 | High refractive index aromatic-based prepolymers | FHIT, PLOD3, AHR | TSHR 4314/4885THRB 4121/4885FAAH 3374/4885 |
| US-20050165246-A1 | High refractive index aromatic-based prepolymer precursors | FHIT, AHR, ITK | TSHR 4384/4885THRB 4351/4885FAAH 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.