Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890380 | 0.87 | KDM2B (0.56) | KDM2BKDM4ELMNA | |
| SCHEMBL31175186 | 0.84 | ALDH1A1 (0.70) | L3MBTL1ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL24873099 | 0.82 | ALDH1A1 (0.66) | POLBALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL24872873 | 0.82 | BCL9 (0.61) | ALDH1A1LMNAMAPTCYP3A4CYP2C9 | |
| SCHEMBL14528293 | 0.79 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KDM2BHSD17B10NPC1 | |
| SCHEMBL611098 | 0.79 | KDM2B (0.48) | ALDH1A1KDM2BKDM4E | |
| SCHEMBL10123430 | 0.79 | KDM2B (0.48) | ALDH1A1KDM2BKDM4E | |
| SCHEMBL4961302 | 0.79 | KDM2B (0.48) | ALDH1A1KDM2BKDM4E | |
| SCHEMBL611097 | 0.79 | KDM2B (0.48) | ALDH1A1KDM2BKDM4E | |
| SCHEMBL30361577 | 0.77 | BCL9 (0.50) | ALDH1A1HSD17B10KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189231-B | Novel cyclic aminophenylalkanoic acid derivative | KYORIN SEIYAKU KK | 2011-05-18 | — | — | CN | disclosed |
| US-20090036489-A1 | Novel Cyclic Aminophenylalkanoic Acid Derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036489-A1 | Novel Cyclic Aminophenylalkanoic Acid Derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-101189231-A | Novel cyclic aminophenylalkanoic acid derivative | KYORIN SEIYAKU KK (JP) | 2008-05-28 | — | — | CN | disclosed |
| EP-1862464-A1 | NOVEL CYCLIC AMINOPHENYLALKANOIC ACID DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2007-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036489-A1 | Novel Cyclic Aminophenylalkanoic Acid Derivative | PPARA, PPARD, PPARG | L3MBTL1 4698/4885POLB 2579/4885ALDH1A1 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.