Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070351 | 0.84 | NOTUM (0.56) | ALDH1A1HSD17B10NPC1MEN1KMT2A | |
| SCHEMBL2069693 | 0.81 | GABRA1 (0.48) | ALDH1A1FKBP1AGABRA1GABRG2GABRB3 | |
| SCHEMBL3897193 | 0.79 | L3MBTL1 (0.63) | ALDH1A1KDM2BL3MBTL1HSD17B10NPC1 | |
| SCHEMBL15630772 | 0.78 | DPP4 (0.51) | ALDH1A1HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2070008 | 0.78 | DPP4 (0.51) | ALDH1A1HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13624219 | 0.78 | HPGD (0.49) | ALDH1A1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL2826490 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMRGPRX4 | |
| SCHEMBL15630696 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HSD17B10NPC1RAB9A | |
| SCHEMBL2849061 | 0.77 | CPB1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL2849059 | 0.77 | CPB1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780210-A1 | NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2007-05-02 | — | — | EP | disclosed |