Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 14/20 | 0.47 |
| ▸ | CDC25B | P30305 | 14/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881338 | 0.90 | PTPN1 (0.46) | PTPN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3883530 | 0.88 | PTGER1 (0.53) | PTGER1PTGER4PTGER3PTGER2AKR1C3 | |
| SCHEMBL3887505 | 0.88 | PTGER1 (0.46) | PTPN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3891271 | 0.88 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2AKR1C3 | |
| SCHEMBL3885358 | 0.86 | PTPN1 (0.46) | PTPN1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3882133 | 0.85 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2AKR1C3 | |
| SCHEMBL3882422 | 0.83 | PPARA (0.49) | PTGER1PTGER4PTGER3PTGER2AKR1C3 | |
| SCHEMBL3884690 | 0.83 | FFAR4 (0.60) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3894526 | 0.82 | PPARG (0.47) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3883909 | 0.82 | PPARG (0.45) | PTGER1PTGER4PTGER3PTGER2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |