SCHEMBL3885358

SCHEMBL3885358

CC(Cc1ccc(OCCc2ccccc2F)c(-c2ccc3cc(O)ccc3c2)c1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 12/20 0.46
PTGER1 P34995 2/20 0.43
PTGER4 P35408 2/20 0.43
PTGER3 P43115 2/20 0.43
PTGER2 P43116 2/20 0.43
PPARA Q07869 2/20 0.43
PPARD Q03181 1/20 0.43
PTPN2 P17706 10/20 0.43
CDC25B P30305 10/20 0.43
PTPN6 P29350 3/20 0.40
FFAR4 Q5NUL3 2/20 0.39
PPARG P37231 2/20 0.39
FFAR1 O14842 1/20 0.39
PLA2G10 O15496 1/20 0.38
PLA2G2A P14555 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3881338 0.94 PTPN1 (0.46) PTPN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3897289 0.86 PTPN1 (0.52) PTPN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3888486 0.86 LTB4R (0.41) PTPN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3883546 0.85 FFAR4 (0.56) PTGER4PTGER3FFAR4FFAR1
SCHEMBL3882546 0.84 TRPA1 (0.44) PTPN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3883504 0.83 AR (0.43) PTPN1PTGER1PTGER4PTGER3PTGER2
SCHEMBL3882422 0.83 PPARA (0.49) PTGER1PTGER4PTGER3PTGER2PPARA
SCHEMBL3884889 0.83 FFAR4 (0.44) PTPN1PPARAPPARDPTPN2CDC25B
SCHEMBL3894526 0.82 PPARG (0.47) PTGER1PTGER4PTGER3PTGER2PPARA
SCHEMBL3883530 0.80 PTGER1 (0.53) PTGER1PTGER4PTGER3PTGER2PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed