Methionine

Methionine

SCHEMBL3897605

CSCC[C@H](N)C(=O)O.NC(N)=S

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.50
NOS2 P35228 4/20 0.50
NOS3 P29474 3/20 0.50
NOS1 P29475 3/20 0.50
BHMT2 Q9H2M3 1/20 0.50
RNPEP Q9H4A4 1/20 0.48
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP2C19 P33261 1/20 0.46
THPO P40225 1/20 0.46
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
CYP1A2 P05177 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL3897598 1.00 BHMT (0.50) BHMTNOS2NOS3NOS1BHMT2
Racemethionine SCHEMBL11790284 0.94 NOS2 (0.53) BHMTNOS2NOS3NOS1BHMT2
Methionine SCHEMBL11790289 0.94 NOS2 (0.53) BHMTNOS2NOS3NOS1BHMT2
Racemethionine SCHEMBL25218893 0.94 BHMT (0.55) BHMTNOS2NOS3NOS1BHMT2
Methionine SCHEMBL27763019 0.94 BHMT (0.55) BHMTNOS2NOS3NOS1BHMT2
Methionine SCHEMBL17926379 0.94 BHMT (0.55) BHMTNOS2NOS3NOS1BHMT2
Racemethionine SCHEMBL27883636 0.92 RNPEP (0.50) BHMTNOS2NOS3NOS1BHMT2
Racemethionine SCHEMBL4408668 0.92 BHMT (0.53) BHMTNOS2NOS3NOS1BHMT2
Methionine SCHEMBL4757668 0.92 BHMT (0.53) BHMTNOS2NOS3NOS1BHMT2
Methionine SCHEMBL22076612 0.92 BHMT (0.53) BHMTNOS2NOS3NOS1BHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130217791-A1 MATERIALS AND PROCESS FOR ENHANCING SELECTIVE SEPARATIONS GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-08-22 US disclosed
US-8425781-B2 Materials and process for enhancing selective separations GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-04-23 US disclosed
US-20090301972-A1 MATERIALS AND PROCESS FOR ENHANCING SELECTIVE SEPARATIONS GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-12-10 US disclosed
WO-2009149334-A2 MATERIALS AND PROCESS FOR ENHANCING SELECTIVE SEPARATIONS GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-12-10 WO disclosed