Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.50 |
| ▸ | HTR3B | O95264 | 5/20 | 0.50 |
| ▸ | HTR3A | P46098 | 5/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901126 | 0.91 | ALDH1A1 (0.67) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL3892980 | 0.90 | ALDH1A1 (0.63) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL3899885 | 0.90 | ALDH1A1 (0.63) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL4202120 | 0.89 | ALDH1A1 (0.72) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL4198172 | 0.89 | ALDH1A1 (0.72) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL3891879 | 0.89 | ALDH1A1 (0.62) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL7061023 | 0.89 | ALDH1A1 (0.69) | ALDH1A1POLBCHRNA7HTR3EHTR3B | |
| SCHEMBL3891877 | 0.88 | ALDH1A1 (0.60) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL3905397 | 0.87 | ALDH1A1 (0.85) | ALDH1A1POLBPTPN1PTPN11CHRNA7 | |
| SCHEMBL7061174 | 0.85 | ALDH1A1 (0.68) | ALDH1A1POLBCHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | claimed |
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | disclosed |