Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | POLB | P06746 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892933 | 0.93 | ALDH1A1 (0.89) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL3898882 | 0.92 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL7062806 | 0.92 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL3892980 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL3899885 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBCHRNA7PTPN1PTPN11 | |
| SCHEMBL3897649 | 0.87 | ALDH1A1 (0.66) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL3891879 | 0.86 | ALDH1A1 (0.62) | ALDH1A1POLBKMT2AMAPTCHRNA7 | |
| SCHEMBL3891877 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTCHRNA7PTPN1 | |
| SCHEMBL7057984 | 0.83 | ALDH1A1 (0.81) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL7059126 | 0.81 | ALDH1A1 (0.69) | ALDH1A1POLBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514450-B2 | Azabicyclic aryl derivatives | NEUROSEARCH A/S (DK) | 2009-04-07 | — | — | US | disclosed |