Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904589 | 0.88 | F10 (0.51) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3897181 | 0.85 | F10 (0.60) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3898352 | 0.85 | F10 (0.58) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3901290 | 0.85 | POLB (0.59) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3901407 | 0.83 | NPC1 (0.60) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14132012 | 0.83 | F10 (0.76) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3898858 | 0.83 | NPC1 (0.62) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3901294 | 0.82 | F10 (0.60) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3910408 | 0.82 | F10 (0.63) | F10POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3902858 | 0.82 | RAB9A (0.58) | F10POLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |