Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | ME3 | Q16798 | 4/20 | 0.60 |
| ▸ | ME2 | P23368 | 3/20 | 0.60 |
| ▸ | ME1 | P48163 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20013063 | 0.93 | MAPT (0.86) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL3835741 | 0.88 | GAA (1.00) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL20644396 | 0.88 | KMT2A (0.78) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL12240583 | 0.88 | GAA (0.81) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL28151038 | 0.88 | ALDH1A1 (0.78) | GAAMAPTALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL23040411 | 0.87 | MAPT (0.78) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9125722 | 0.87 | ALDH1A1 (0.75) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL3965662 | 0.86 | GAA (0.79) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL2543995 | 0.86 | GAA (0.79) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL13114782 | 0.83 | MAPT (0.71) | GAAMAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758385-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LAB LTD (IN) | 2018-03-28 | — | — | EP | claimed |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | MSN LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | claimed |
| EP-2758385-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN Laboratories Limited (IN) | 2014-07-30 | — | — | EP | claimed |
| WO-2013042138-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-03-28 | — | — | WO | claimed |
| WO-2019077627-A1 | A PROCESS FOR THE MANUFACTURE OF POSACONAZOLE | METROCHEM API PVT LTD. (IN) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019077627-A1 | A PROCESS FOR THE MANUFACTURE OF POSACONAZOLE | METROCHEM API PVT LTD. (IN) | 2019-04-25 | — | — | WO | disclosed |
| EP-2758385-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LAB LTD (IN) | 2018-03-28 | — | — | EP | disclosed |
| EP-2758385-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LAB LTD (IN) | 2018-03-28 | — | — | EP | disclosed |
| US-9102664-B2 | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED (IN) | 2015-08-11 | — | — | US | disclosed |
| US-9102664-B2 | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED (IN) | 2015-08-11 | — | — | US | disclosed |
| US-9102664-B2 | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED (IN) | 2015-08-11 | — | — | US | disclosed |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | MSN LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | disclosed |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | MSN LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | disclosed |
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | MSN LABORATORIES LIMITED (IN) | 2014-11-20 | — | — | US | disclosed |
| EP-2758385-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN Laboratories Limited (IN) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013042138-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013042138-A2 | PROCESS FOR THE PREPARATION OF TRIAZOLE ANTIFUNGAL DRUG, ITS INTERMEDIATES AND POLYMORPHS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-03-28 | — | — | WO | disclosed |
| WO-2009141837-A2 | PROCESS FOR PREPARING POSACONAZOLE AND INTERMEDIATES THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343285-A1 | Process for the Preparation of Triazole Antifungal Drug, Its Intermediates and Polymorphs Thereof | CYP3A4, CYP51A1, CYP1B1 | GAA 505/4885MAPT 1385/4885ALDH1A1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.