Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20013063 | 0.90 | MAPT (0.86) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL2543995 | 0.90 | GAA (0.79) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL12240583 | 0.88 | GAA (0.81) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3835741 | 0.88 | GAA (1.00) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL3898025 | 0.86 | GAA (1.00) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL20644396 | 0.85 | KMT2A (0.78) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL11145831 | 0.85 | ALDH1A1 (0.76) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL28151038 | 0.85 | ALDH1A1 (0.78) | GAANPSR1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL23040411 | 0.85 | MAPT (0.78) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL7885204 | 0.82 | GAA (0.70) | GAANPSR1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141837-A2 | PROCESS FOR PREPARING POSACONAZOLE AND INTERMEDIATES THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |