Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20893390 | 1.00 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| Methylene Chloride SCHEMBL28081516 | 0.88 | POLB (0.53) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL28054665 | 0.87 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL6899788 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL1467517 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL3141725 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL135177 | 0.85 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL47049 | 0.85 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL3576321 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 | |
| SCHEMBL133363 | 0.85 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2ALDH1A1PDE8BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |